Drug Metabolites

  1. militarydefenselawyers319Marijuana.
    1. Main psychoactive ingredient is delta 9-tetrahydrocannabinol (short name: delta-9 THC)
    2. Main metabolite (waste product) of delta-9 THC is delta 9-tetrahydrocannabinol-9-carboxylic acid (short name: 9-carboxyl THC). This is the metabolite tested for within DOD.
    3. 9-carboxyl THC is not psychoactive, and is not the only metabolite. 10-90% percent of the total number of metabolites are 9-carboxyl THC.
    4. 9-carboxyl THC is found in urine only when human body metabolizes marijuana; the human body cannot naturally produce 9-carboxyl THC.
  2. Cocaine.
    1. Main metabolite is benzoylecgonine (BZE).
      1. This is the metabolite tested for within DOD
      2. BZE is found in urine when human body metabolizes cocaine; it cannot be naturally produced by human body, but can be produced by introducing cocaine directly into urine (no metabolizing needed).
    2. Secondary metabolite is ecgonine methyl ester (EME).
      1. This metabolite is not tested for within DOD
      2. EME dissipates from the body more quickly than BZE.
      3. EME is found in urine when human body metabolizes cocaine; it cannot be naturally produced by human body and cannot be produced by introducing cocaine directly into urine